Biological fluid stabilizing composition and method of use thereof
OwnerJack A. Maggiore, Barbara R. Grzedainventors
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Abstract
An aqueous biological fluid preserving composition consists essentially of a chelating agent, such as EDTA, and a cell lysing amount of a cell lysing agent, such as an alcohol. The biological fluid preserving composition can also include a preservative, an antifreeze agent and a non-chelating anticoagulant. The aqueous biological fluid preserving composition is useful for preserving biological fluids collected for later quantitative determination of protein components such as hormones.
Claims34
An aqueous biological fluid preserving composition suitable for preservation of a biological fluid specimen consisting essentially of a chelating agent and a cell lysing amount of a cell lysing agent in water.
An aqueous biological fluid preserving composition suitable for preservation of a biological fluid specimen consisting essentially of:
- a) about 0.05 to about 0.5 weight percent of a chelating agent;
- b) about 5 to about 25 weight percent of a cell lysing agent;
- c) up to about 0.1 weight percent of a preservative;
- and
- d) the remainder being water.
A method of preserving a protein-containing biological fluid specimen comprising the sequential steps of:
- a) providing a sealable container, suitable for storing or transporting a biological fluid sample;
- b) combining in said container a biological fluid specimen and an aqueous biological fluid preserving solution consisting essentially of a chelating agent and a cell lysing amount of a cell lysing agent in water;
- and
- c) sealing the container.
Dependencies are inferred from the claim text.