Human cDNAs and proteins and uses thereof
AssigneeGenset S.A.
InventorsStephane Bejanin, Hiroaki Tanaka
Life of this patent
Estimating the term…
Abstract
The invention concerns GENSET polynucleotides and polypeptides. Such GENSET products may be used as reagents in forensic analyses, as chromosome markers, as tissue/cell/organelle-specific markers, in the production of expression vectors. In addition, they may be used in screening and diagnosis assays for abnormal GENSET expression and/or biological activity and for screening compounds that may be used in the treatment of GENSET-related disorders.
Claims13
An isolated polynucleotide, comprising a nucleic acid sequence selected from the group consisting of:
- a) a polynucleotide of SEQ ID NO:
- 53, or of a human cDNA of deposited clone 182-14-3-0-C12-F, encoding at least any single integer from 6 to 500 amino acids of SEQ ID NO:
- 54;
- b) a polynucleotide of SEQ ID NO:
- 53, or of a human cDNA of deposited clone 182-14-3-0-C12-F, encoding the signal peptide sequence of SEQ ID NO:
- 54;
- c) a polynucleotide of SEQ ID NO:
- 53, or of a human cDNA of deposited clone 182-14-3-0-C12-F, encoding a mature polypeptide sequence of SEQ ID NO:
- 54;
- d) a polynucleotide of SEQ ID NO:
- 53, or of a human cDNA of deposited clone 182-14-3-0-C12-F, encoding a full length polypeptide sequence of SEQ ID NO:
- 54;
- e) a polynucleotide of SEQ ID NO:
- 53, or of a human cDNA of deposited clone 182-14-3-0-C12-F, encoding a polypeptide sequence of a biologically active fragment of SEQ ID NO:
- 54;
- f) a polynucleotide encoding a polypeptide sequence of at least any single integer from 6 to 500 amino acids of SEQ ID NO:
- 54 or of a polypeptide encoded by a human cDNA of deposited clone 182-14-3-0-C12-F;
- g) a polynucleotide encoding a polypeptide sequence of a signal peptide of SEQ ID NO:
- 54 or of a signal peptide encoded by a human cDNA of deposited clone 182-14-3-0-C12-F;
- h) a polynucleotide encoding a polypeptide sequence of a mature polypeptide of SEQ ID NO:
- 54 or of a mature polypeptide encoded by a human cDNA of deposited clone 182-14-3-0-C12-F;
- i) a polynucleotide encoding a polypeptide sequence of a full length polypeptide of SEQ ID NO:
- 54 or of a mature polypeptide encoded by a human cDNA of deposited clone 182-14-3-0-C12-F;
- j) a polynucleotide encoding a polypeptide sequence of a biologically active polypeptide of SEQ ID NO:
- 54, or of a biologically active polypeptide encoded by a human cDNA of deposited clone 182-14-3-0-C12-F;
- k) a polynucleotide of any one of a) through j) further comprising an expression vector;
- l) a host cell recombinant for a polynucleotide of a) through k) above;
- m) a non-human transgenic animal comprising the host cell of k);
- and
- n) a polynucleotide of a) through j) further comprising a physiologically acceptable carrier.
A polypeptide comprising an amino acid sequence selected from the group consisting of:
- a) any single integer from 6 to 500 amino acids of SEQ ID NO:
- 54 or of a polypeptide encoded by a human cDNA of deposited clone 182-14-3-0-C12-F;
- b) a signal peptide sequence of SEQ ID NO:
- 54 or encoded by a human cDNA of deposited clone 182-14-3-0-C12-F;
- c) a mature polypeptide sequence of SEQ ID NO:
- 54 or encoded by a human cDNA of deposited clone 182-14-3-0-C12-F;
- d) a full length polypeptide sequence of SEQ ID NO:
- 54 or encoded by a human cDNA of deposited clone 182-14-3-0-C12-F;
- and
- e) a polypeptide of a) through d) further comprising a physiologically acceptable carrier.
Dependencies are inferred from the claim text.