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AssigneeNgk Spark Plug Co., Ltd.
InventorsToshihiro Kasuga, Mitsuo Niinomi, Kohji Okada
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An osteoconductive biomaterial including a metallic substrate and a metal oxide layer on a surface of the metallic substrate and which contains, at least on a portion of the surface of the metal oxide layer opposite the substrate, at least one chemical species selected from —PO4H2, —TiOH, —ZrOH, —NbOH, —TaOH and —SiOH. The metallic substrate preferably contains titanium. The metal oxide layer may be formed by heating the substrate. At least on a surface of the metal oxide layer, a specific chemical species can be formed by soaking the substrate in a phosphate buffer or a similar solution and subjecting the substrate to hydrothermal treatment at a temperature of 100° C. or higher and a pressure of 0.1 MPa or higher. The thickness of the metal oxide layer can be, for example, about 5 μm.
An osteoconductive biomaterial comprising a substrate having a surface, said surface comprising an oxide material, wherein at least a portion of an exterior surface of said oxide material contains at least one species selected from the group consisting of —PO4H2, —TiOH, —ZrOH, —NbOH, —TaOH and —SiOH.
An osteoconductive biomaterial comprising a metallic substrate and a metal oxide layer provided on a surface of said metallic substrate, wherein at least a portion of a surface of said metal oxide layer opposite the substrate contains at least one chemical species selected from the group consisting of —PO4H2, —TiOH, —ZrOH, —NbOH, —TaOH and —SiOH.
An osteoconductive biomaterial comprising a oxide ceramic substrate, wherein at least a portion of an exterior surface of said oxide ceramic substrate contains at least one chemical species selected from the group consisting of —PO4H2, —TiOH, —ZrOH, —NbOH, —TaOH and —SiOH.
An osteoconductive biomaterial comprising a non-oxide ceramic substrate and an oxide ceramic layer provided on a surface of said non-oxide ceramic substrate, wherein at least a portion of a surface of said oxide ceramic layer opposite the substrate contains at least one chemical species selected from the group consisting of —PO4H2, —TiOH, —ZrOH, —NbOH, —TaOH and —SiOH.
Dependencies are inferred from the claim text.