Use of oligosaccharides to stimulate beta-endorphin production
OwnerFrederic Bonte, Marc Dumas +2inventors
InventorsFrederic Bonte, Marc Dumas, Stephane Lhermite, Alex Saunois
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Abstract
The invention concerns the use of at least an oligosaccharide comprising 2 to 6 sugars and containing at least 2 galactose units, preferably 2 vicinal end-of-chain galactose motifs, or a plant extract containing same, as a cosmetic or dermatological agent, in particular for stimulating the beta-endorphin production in the skin. The invention enables to provide care for sensitive skins, in particular to fight against skin sensitivity, uncomfortable reactions, to provide sensations of well-being, and to produce a local analgesic action.
Claims10
Use of at least one oligosaccharide comprising from 2 to 6 sugars and containing at least 2 galactose units, preferably 2 vicinal galactose units and more preferably two vicinal galactose units at the end of the chain, or of a plant extract containing it, as a cosmetic or dermatological agent for stimulating the production of beta-endorphin in the skin.
Use according to one of the preceding claims, characterized in that the oligosaccharide or the plant extract, expressed by dry weight in this case, is present at a concentration of between 0.0001% and 10% by weight of a cosmetic or dermatological composition, based on the total weight of said composition.
Use according to one of the preceding claims, characterized in that the oligosaccharide or the plant extract containing it, expressed by dry weight in this case, is present at a concentration of between 0.01% and 5% by weight of a cosmetic or dermatological composition containing it, based on the total weight of said composition.
Use according to one of the preceding claims, characterized in that the above-mentioned oligosaccharide, or a plant extract containing it, is combined with another cosmetically or dermatologically acceptable active substance preferably selected from the group consisting of vitamin A and its esters, particularly vitamin A palmitate;
- an alpha-hydroxy acid, particularly salicylic acid and its derivatives or lactic, glycolic or malic acid;
- an inhibitor of the enzyme PLA2, such as an extract of the plant Phellodendron amurense or the plant Azadirachta indica;
- a substance with anti-inflammatory activity, such as 18B-glycyrrhetinic acid, an extract of the plant Glycyrrhiza glabra;
- a substance with immunomodulating activity, such as a glycan;
- a surfactant, particularly of the laurylsulfate family;
- an alkaloid substance, preferably a bisbenzylisoquinoline and particularly oxyacanthine or cepharanthine;
- a PAF inhibitor, particularly a Gingko bilobe extract;
- and an inhibitor of PGE2 enzymes.
Use according to any one of the preceding claims, characterized in that the above-mentioned oligosaccharide, or a plant extract containing it, is applied to the skin in order to care for sensitive skin, notably to reduce or eliminate uncomfortable reactions, provide a sensation of well-being or exert a local analgesic action.
Dependencies are inferred from the claim text.