Synergistic composition of trans-tetracos-15-enoic acid and Apocynin and method of treatment for hepatotoxicity
AssigneeCouncil of Scientific Research
InventorsSukhdev Swami Handa, Om Parkash Suri, V.N. Gupta, Krishan Avtar Suri, Naresh Kumar Satti, Vikram Bhardwaj, Bupinder Singh, Bal Krishan Chandan
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Abstract
The present invention relates to a synergistic hepatoprotective pharmaceutical composition comprising an effective amount of trans-tetracos-15-enoic acid (TCA) and Apocynin (APO), the present invention also relates to a method of treatment for hepatotoxicity in mammals and humans.
Claims34
A synergistic pharmaceutical composition having enhanced hepatoprotective activity on subjects, said composition comprising an effective amount of:
- (a) trans-tetracos-15-enoic acid (TCA) obtained from the plant Indigofera tinctoria;
- (b) Apocynin (APO) obtained from the plants Apocyanum cannabium and A. androsaemifolium;
- and
- (c) the ratio of APO and TCA is in the range of 3:1 to 1:3.
A method of treating subjects with liver disorders with an effective amount of synergistic pharmaceutical composition to induce enhanced hepatoprotective activity, said composition comprising:
- (a) trans-tetracos-15-enoic acid (TCA) obtained from the plant Indigofera tinctoria;
- (b) Apocynin (APO) obtained from the plants Apocyanum cannabium and A. androsaemifolium;
- and
- (c) the ratio of APO and TCA is in the range of 3:1 to 1:3.
Dependencies are inferred from the claim text.