Plant-derived anti-parasitic and antifungal compounds and methods of extracting the compounds
OwnerChristopher O. Okunji, Maurice M. Iwu +4inventors
InventorsCHRISTOPHER O. OKUNJI, MAURICE M. IWU, JOAN E. JACKSON, JOHN D. TALLY JR., CYRUS BACCHI, JOHNSON F. AYAFOR
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Abstract
Provided are biologically active extracts from Aframomum aulocacarpus, Aframomum danellii, Dracaena arborea, Eupatorium odoratum, Glossocalyx brevipes and Napoleonaea imperialis which are suitable for use in treating fungal and protozoa diseases.
Claims29
A biologically active extract from at least one plant selected from the group consisting of Aframomum aulocacarpus, Aframomum danellii, Dracaena arborea, Eupatorium odoratum, Glossocalyx brevipes and Napoleonaea imperialis.
A method of preparing a biologically active extract from at least one plant selected from the group consisting of Aframomum aulocacarpus, Aframomum danellii, Dracaena arborea, Eupatorium odoratum, Glossocalyx brevipes and Napoleonaea imperialis, the method comprising:
- pulverizing at least a part of said plant;
- selecting a solvent which dissolves or solubilizes a desired biologically active compound from said plant;
- combining said solvent and said pulverized plant to extract said desired biologically active compound;
- and
- removing said solvent from said extract of said desired biologically active compound.
A topical composition composition comprising a biologically active extract from at least one plant selected from the group consisting of Aframomum aulocacarpus, Aframomum danellii, Dracaena arborea, Eupatorium odoratum, Glossocalyx brevipes and Napoleonaea imperialis in a topical carrier.
An oral composition comprising a biologically active extract from at least one plant selected from the group consisting of Aframomum aulocacarpus, Aframomum danellii, Dracaena arborea, Eupatorium odoratum, Glossocalyx brevipes and Napoleonaea imperialis in an oral carrier.
An intravenous composition comprising a biologically active extract from at least one plant selected from the group consisting of Aframomum aulocacarpus, Aframomum danellii, Dracaena arborea, Eupatorium odoratum, Glossocalyx brevipes and Napoleonaea imperialis in an intravenous carrier.
A method of treating a fungal or protozoal disease in a mammal comprising applying a biologically active extract from at least one plant selected from the group consisting of Aframomum aulocacarpus, Aframomum danellii, Dracaena arborea, Eupatorium odoratum, Glossocalyx brevipes and Napoleonaea imperialis.
A compound comprising:
- 4
A compound comprising:
- 5
- C17H18O4
- 286.32
- 286.120509
- C 71.3% H 6.3% 0 22.4%
A compound comprising:
- 6
Dependencies are inferred from the claim text.