Pharmaceutical preparations and their manufacture
OwnerJohn Nicholas Staniforth, Michael John Tobyn +2inventors
InventorsJohn Nicholas Staniforth, Michael John Tobyn, Cheryl Julia Clinch, Robert Price
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Abstract
A method for making a composition comprising active particles comprising an active substance comprises the steps of a) providing an emulsion having a dispersed phase comprising a solution of the active substance in a solvent and b) inducing the formation, in the emulsion, of solid particles comprising the active substance. The particles may be isolated from the emulsion. Active particles having a normalized kurtosis of at least 5 and a mean diameter of less than 100 μm are provided.
Claims42
A method of making a composition comprising active particles comprising an active substance, the method comprising the steps of:
- a) providing an emulsion having a dispersed phase comprising a solution of the active substance in a solvent;
- and
- b) inducing the formation, in the emulsion, of solid particles comprising the active substance, thereby forming an emulsion comprising the solid active particles.
A method of making a composition comprising active particles substantially as described herein.
A composition comprising active particles comprising an active substance and having a median diameter of less than 100 μm and a normalised Kurtosis of at least 5.
A composition comprising active particles substantially as described herein.
Dependencies are inferred from the claim text.