Drug delivery system for poorly water soluble drugs
OwnerEsteban Chornet, Claudia Ishizawa +1inventors
InventorsEsteban Chornet, Claudia Ishizawa, Severian Dumitriu
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Abstract
The present invention relates to a method for modifying the solubilization rates of poorly water soluble drugs, using a chitosan-xanthan hydrogel. In addition, the present invention relates to a process for the preparation of chitosan-xanthane hydrogels as well as for the preparation of hydrogels comprising a poorly water soluble drug.
Claims17
A drug delivery system comprising a chitosan-xanthane hydrogel, said hydrogel including in its matrix a poorly water soluble drug which upon swelling of said hydrogel in an aqueous medium becomes at least partially solubilized and releasable therefrom.
A method for modifying the solubilization rate of a poorly water soluble drug which comprises the step of including said poorly water soluble drug in a hydrogel composed of a chitosan-xanthane microstructure, said microstructure governing said solubilization rate.
Dependencies are inferred from the claim text.