Immunostimulating coating for surgical devices
AssigneeBrennen Medical, Inc.
InventorBarbara K. Klein
Life of this patent
Estimating the term…
Abstract
The present invention discloses an immunostimulating agent that may be applied to various surgical devices to promote rapid healing and the ready acceptance and integration of the surgical devices with the body tissues at the surgical site.
Claims44
A biocompatible surgical device for implantation at a surgical site having applied thereto a beta D glucan composition.
A biocompatible surgical device for implantation at a surgical site comprising:
- a surgical device fabricated from a material chosen from a group comprising polyester, polypropylene, polyethylene, polyurethane, polyolefin, polyvinyl chloride, silk, elastin, keratin, cartilage, ceramics, polytetrafluoroethylene, rayon, gortex, cellulose, collagen matrix, silicone, titanium, gold, silver, stainless steel, graphite, diamond and carbon fiber composite materials, said surgical device having applied thereto an immunostimulating agent.
An organic biocompatible surgical device for implantation at a surgical site for reinforcing said surgical site having applied thereto an imunostimulating agent.
A biocompatible surgical device for implantation at a surgical site comprising a device chosen from a group comprising coronary appliances, tissue augmentation devices, nasal reconstruction materials, screws, plates, pins, artificial joints, dental implants, and sutures, the surgical device having applied thereto a cereal derived beta D glucan composition.
A method of applying an imunostimulating agent to a biocompatible surgical device comprising the steps of:
- a. preparing an aqueous solution comprising a beta D glucan;
- b. immersing a pre-selected surgical device in said aqueous solution;
- and
- c. evaporating the water component of the aqueous solution.
A method of applying an imunostimulating agent to a biocompatible surgical device comprising the steps of:
- a. preparing an aqueous solution comprising a beta D glucan;
- b. placing said aqueous solution in a drying tray;
- c. evaporating the water component of said aqueous solution to produce a sheet of beta D glucan;
- and
- d. applying said sheet of beta D glucan to said surgical device.
A method of applying an immunostimulating agent to a biocompatible surgical device comprising the steps of:
- applying a suitable solvent to the biocompatible surgical device;
- applying to the wedded biocompatible surgical device a β-D-glucan powder such that the β-D-glucan powder dissolves into the solvent to form a substantially uniform coating upon the biocompatible surgical device;
- and
- evaporating the solvent from the substantially uniform coating of β-D-glucan upon the biocompatible surgical device.
A method of applying an immunostimulating agent to a biocompatible surgical device comprising the steps of:
- preparing an aqueous solution comprising a β-D-glucan;
- placing the aqueous solution of β-D-glucan in a spraying mechanism;
- coating a predetermined portion of the surface of the biocompatible surgical device with the aqueous β-D-glucan solution by spraying the aqueous solution onto the surface of the biocompatible surgical device;
- and
- drying the aqueous solution of β-D-glucan deposited on the surface of the biocompatible surgical device.
A method of applying an immunostimulating agent to a biocompatible surgical device comprising the steps of:
- preparing an aqueous solution comprising a β-D-glucan;
- placing said aqueous solution in an electrostatically charged spraying device;
- placing the biocompatible surgical device upon a support structure having an electrostatic charge opposite that of the spraying device;
- spraying the electrostatically charged aqueous solution onto the oppositely charged biocompatible surgical device so as to form a coating thereon;
- and,
- drying the aqueous solution on the surface of the biocompatible surgical device.
A method of applying an immunostimulating agent to a biocompatible surgical device comprising the steps of:
- applying an aqueous solution comprising β-D-glucan to the surface of a biocompatible surgical device;
- drawing a vacuum around the coated biocompatible surgical device;
- removing the biocompatible surgical device from the vacuum;
- and,
- drying the aqueous solution on the surface of the biocompatible surgical device.
A method of promoting the acceptance of a surgical device into the tissues into which the surgical device is implanted, the method comprising the step of applying an immunostimulating agent to the surgical device before implantation.
A method of promoting the acceptance of a surgical device into the tissues into which the surgical device is implanted, the method comprising the step of applying an immunostimulating agent comprising a β-D-glucan to the surgical device before implantation.
A method of promoting the acceptance of a surgical device into the tissues into which the surgical device is implanted, the method comprising the step of applying an immunostimulating agent comprising a cereal-derived β-D-glucan to the surgical device before implantation.
A method of promoting the acceptance of a surgical device into the tissues into which the surgical device is implanted, the method comprising the step of applying an immunostimulating agent to the surgical device before implantation at a surgical site, the immunostimulating agent comprising a β-D-glucan derived from one of a group comprising yeast, fungi, cereal grains, and bacteria.
Dependencies are inferred from the claim text.