Nonoral preparation having three-layer structure
OwnerKanji Takadainventor
Life of this patent
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Abstract
The purpose of the present invention is to provide micro- or mili-capsules and film preparations having not only sustained-release function but also targeting and adhesive functions with approximately 100% loading efficiency of the objective substance. The present invention provides a parenteral preparation having three layers structure of; basement layer composed of polymer; carrying layer that contains objective substances selected from drugs, aroma chemicals, mosquito propellant, dyes, cells or antigens; and surface layer, and in which the carrying layer is sandwiched between the basement layer and the surface layer.
Claims11
A parenteral preparation having three layers structure of;
- basement layer composed of polymer;
- carrying layer that contains objective substances selected from drugs, aroma chemicals, mosquito propellant, dyes, cells or antigens;
- and surface layer, and in which the carrying layer is sandwiched between the basement layer and the surface layer.
A method of producing a parenteral preparation, which comprises the steps of:
- forming micron- or mili-size dents on the basement layer made of a film prepared by using water-insoluble polymer or biodegradable polymer;
- filling an objective substance selected from drugs, aroma chemicals, mosquito propellant, dyes, cells or antigens in the said dents;
- sealing the openings of the dents by adhering the surface layer made of a polymer film on which adhesive glue is painted onto the top of the dents;
- and
- cutting the obtained three-layered film into micron- or mili size.
A method of producing a parenteral preparation, which comprises the steps of:
- spreading a mixture of an objective substance selected from drugs, aroma chemicals, mosquito propellant, dyes, cells or antigens and an adhesive agent on the basement layer made of a film prepared by using water-insoluble polymer or biodegradable polymer;
- covering the top of the thus spread mixture with the surface layer made of polymer film;
- and
- sealing and punching out the three layered polymer film with a pre-heated hole puncher having a μm or mm size holes.
Dependencies are inferred from the claim text.