Dermatological application with solidified fat compositions
AssigneeFoamix Ltd.
InventorsMeir Eini, Dov Tamarkin
Life of this patent
Estimating the term…
Abstract
A pharmaceutical or cosmetic carrier or composition for topical application characterized by rheological properties which render the carrier or composition semi-solid at rest and a liquid upon application of shear forces thereto. The composition or carrier are prepared by mixing 1-25 percent of a solidifying agent and 75-99 percent of a hydrophobic solvent, by weight, wherein at least one of them has therapeutic or cosmetic benefits, in the presence or absence of a biologically active substance.
Claims103
A pharmaceutical or cosmetic carrier comprising, by weight, 1-25 percent of a solidifying agent and 75-99 percent of a hydrophobic solvent.
A method of preparing a pharmaceutical or cosmetic carrier, the method comprising the steps of:
- (a) mixing a hydrophobic solvent and a solidifying agent at a temperature above a melting temperature of said solidifying agent so as to obtain a mixture containing 75-99 percent of said hydrophobic solvent by weight and 1-25 percent of said solidifying agent by weight;
- and
- (b) cooling the mixture.
A pharmaceutical or cosmetic composition comprising, by weight, 1-25 percent of a solidifying agent and 75-99 percent of a hydrophobic solvent, wherein at least one of said solidifying agent and said hydrophobic solvent has a therapeutic or cosmetic beneficial effect.
A pharmaceutical or cosmetic composition comprising:
- (a) a pharmaceutical or cosmetic carrier containing, by weight, 1-25 percent of a solidifying agent and 75-99 percent of a hydrophobic solvent;
- and
- (b) a therapeutically or cosmetically effective amount of a biologically active substance.
A method of preparing a pharmaceutical or cosmetic composition, the method comprising the steps of
- (a) mixing a hydrophobic solvent and a solidifying agent at a temperature above a melting temperature of said solidifying agent so as to obtain a pharmaceutical or cosmetic mixture containing 75-99 percent of said hydrophobic solvent by weight and 1-25 percent of said solidifying agent by weight;
- and
- (b) further mixing into said carrier mixture a therapeutically or cosmetically effective amount of a biologically active substance.
A method of treating a disease or disorder of a skin or a mucosal membrane comprising the step of topically administrating to said skin or said mucosal membrane a pharmaceutical or cosmetic composition containing, by weight, 1-25 percent of a solidifying agent and 75-99 percent of a hydrophobic solvent, wherein at least one of said solidifying agent and said hydrophobic solvent has a therapeutic or cosmetic beneficial effect.
A method of treating a disease or disorder of a skin or a mucosal membrane comprising the step of topically administrating thereto a pharmaceutical or cosmetic composition containing:
- (a) a pharmaceutical or cosmetic carrier containing, by weight, 1-25 percent of a solidifying agent and 75-99 percent of a hydrophobic solvent;
- and
- (b) a therapeutically or cosmetically effective amount of a biologically active substance.
Dependencies are inferred from the claim text.