Antibodies directed to PDGFD and uses thereof
AssigneeAmgen Fremont Inc.
InventorsJose R. F. Corvalan, Xiao-Chi Jia, Xiao Feng, Xiao-dong Yang, Francine Chen, Gadi Gazit, Richard Weber, Binyam Bezabeh
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AssigneeAmgen Fremont Inc.
InventorsJose R. F. Corvalan, Xiao-Chi Jia, Xiao Feng, Xiao-dong Yang, Francine Chen, Gadi Gazit, Richard Weber, Binyam Bezabeh
Estimating the term…
The present invention is related to antibodies directed to the antigen PDGFD and uses of such antibodies. In particular, in accordance with the present invention, there are provided fully human monoclonal antibodies directed to the antigen PDGFD. Nucelotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3, are provided. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also provided.
A human monoclonal antibody that binds to PDGFD and comprises a heavy chain amino acid sequence selected from the group consisting of SEQ ID NOS:
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