Formulation and manufacturing process for coenzyme Q10 soft gel capsules
AssigneeSoft Gel Technologies, Inc.
InventorsRonald G. Udell, Yousry M.A. Naguib, Siva P. Hari
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Abstract
A soft gelatine capsule formulation for improved manufacturing of Coenzyme Q10, comprising Coenzyme Q10 in a thixatropic gelatine carrier capable of admixing without heating with Coenzyme Q10, and capable of keeping Coenzyme Q10 in suspension at ambient temperature.
Claims7
A composition comprising Coenzyme Q10 in combination with an antioxidant in a thixatropic gelatine carrier for manufacturing soft gel capsules at a temperature of about 27° C. to about 30° C. containing a stable uniform suspension of Coenzyme Q10.
A process of manufacturing soft gel capsules containing an improved formulation of Coenzyme Q10, said process per capsule including:
- (a) heating 50 to 500 mg of a thixatropic gelatine carrier to a temperature from about 27° C. to about 30° C.;
- (b) blending in a container under vacuum the heated thixotropic gelatine carrier, 30 to 100 mg of Coenzyme Q10, and 10 to 100 IU Vitamin E;
- ( c) cooling the blended mixture to a temperature of about 23° C. to 28° C.;
- (d) mixing the cooled mixture under a nitrogen blanket;
- and
- (e) encapsulate the mixed, cooled mixture in a soft gel capsule.
Dependencies are inferred from the claim text.