Synergistically uv-photoprotecting mixed sunscreen compositions
AssigneeSociete L'Oreal S.A.
InventorDidier Candau
Life of this patent
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Abstract
Topically applicable cosmetic/dermatological sunscreen composition well suited for the enhanced UV-photoprotection of human skin and/or hair, contain synergistically UV-APPD-enhancing amounts of (i) at least one UV-screening silicon compound having a benzotriazole functional group substituent, (ii) at least one UV-screening dibenzoylmethane compound, and (iii) at least one UV-screening amino-substituted 2-hydroxybenzophenone compound having the following structural formula (III): 1 formulated into (iv) a topically applicable, cosmetically/dermatologically acceptable vehicle, diluent or carrier therefor.
Claims33
A topically applicable cosmetic/dermatological sunscreen composition suited for the UV-photoprotection of human skin and/or hair, comprising synergistically UV-APPD-enhancing amounts of (i) at least one UV-screening silicon compound having a benzotriazole functional group substituent, (ii) at least one UV-screening dibenzoylmethane compound, and (iii) at least one UV-screening amino-substituted 2-hydroxybenzophenone compound having the following structural formula (III):
- 14
- in which R1 and R2, which may be identical or different, are each a hydrogen atom, a C1-C20 alkyl radical, a C2-C10 alkenyl radical, a C3-C10 cycloalkyl radical or a C3-C10 cycloalkenyl radical, with the proviso that R1 and R2 can together form, with the nitrogen atom to which they are bonded, a 5- or 6-membered heterocyclic ring member;
- R3 and R4, which may be identical or different, are each a C1-C20 alkyl radical, a C2-C10 alkenyl radical, a C3-C10 cycloalkyl radical, a C3-C10 cycloalkenyl radical, a C1-C12 alkoxy radical, a (C1-C20)alkoxycarbonyl radical, a C1-C12 alkylamino radical, a di(C1-C12)alkylamino radical, an aryl radical or a heteroaryl radical which is optionally substituted, or a water-solubilizing substituent selected from among a carboxylate group, a sulfonate group or an ammonium residue;
- X′ is a hydrogen atom or a —COOR5 or —CONR6R7 radical;
- R5, R6 and R7, which may be identical or different, are each a hydrogen atom, a C1-C20 alkyl radical, a C2-C10 alkenyl radical, a C3-C10 cycloalkyl radical, a C3-C10 cycloalkenyl radical, a —(Y′O)o—Z′ radical or an aryl radical;
- Y′ is —(CH2)2—, —(CH2)3—, —(CH2)4— or —CH—(CH3)—CH2—;
- Z′ is —CH2—CH3, —CH2CH2CH3, —CH2—CH2—CH2—CH3 or —CH(CH3)—CH3;
- m′ is an integer ranging from 0 to 3;
- n′ is an integer ranging from 0 to 3;
- and o is an integer ranging from 1 to 2, formulated into (iv) a topically applicable, cosmetically/dermatologically acceptable vehicle, diluent or carrier therefor.
A regime or regimen for photoprotecting human skin, and/or hair against the deleterious effect of ultraviolet irradiation, comprising topically applying thereon an effective amount of a cosmetic/dermatological sunscreen composition which comprises synergistically UV-APPD-enhancing amounts of (i) at least one UV-screening silicon compound having a benzotriazole functional group substituent, (ii) at least one UV-screening dibenzoylmethane compound, and (iii) at least one UV-screening amino-substituted 2-hydroxybenzophenone compound having the following structural formula (III):
- 23
- in which R1 and R2, which may be identical or different, are each a hydrogen atom, a C1-C20 alkyl radical, a C2-C10 alkenyl radical, a C3-C10 cycloalkyl radical or a C3-C10 cycloalkenyl radical, with the proviso that R1 and R2 can together form, with the nitrogen atom to which they are bonded, a 5- or 6-membered heterocyclic ring member;
- R3 and R4, which may be identical or different, are each a C1-C20 alkyl radical, a C2-C10 alkenyl radical, a C3-C10 cycloalkyl radical, a C3-C10 cycloalkenyl radical, a C1-C12 alkoxy radical, a (C1-C20)alkoxycarbonyl radical, a C1-C12 alkylamino radical, a di(C1-C12)alkylamino radical, an aryl radical or a heteroaryl radical which is optionally substituted, or a water-solubilizing substituent selected from among a carboxylate group, a sulfonate group or an ammonium residue;
- X′ is a hydrogen atom or a —COOR5 or —CONR6R7 radical;
- R5, R6 and R7, which may be identical or different, are each a hydrogen atom, a C1-C20 alkyl radical, a C2-C10 alkenyl radical, a C3-C10 cycloalkyl radical, a C3-C10 cycloalkenyl radical, a —(Y′O)o—Z′ radical or an aryl radical;
- Y′ is —(CH2)2—, —(CH2)3—, —(CH2)4— or —CH—(CH3)—CH2—;
- Z′ is —CH2—CH3, —CH2CH2CH3, —CH2—CH2—CH2—CH3 or —CH(CH3)—CH3;
- m′ is an integer ranging from 0 to 3;
- n′ is an integer ranging from 0 to 3;
- and o is an integer ranging from 1 to 2, formulated into (iv) a topically applicable, cosmetically/dermatologically acceptable vehicle, diluent or carrier therefor.
Dependencies are inferred from the claim text.