Formulations containing an anticholinergic drug for the treatment of chronic obstructive pulmonary disease
AssigneeChiesi Farmaceutici S.p.A.
InventorsDavid Lewis, David Ganderton, Brian Meakin, Gaetano Brambilla, Alessandra Ferraris
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Abstract
Formulations for the administration through pressurized metered dose aerosol inhalers containing an anticholineric drug in solution in a hydrofluorocarbon propellant, a cosolvent and a low volatility component, and the use thereof in chronic obstructive pulmonary disease.
Claims7
A pharmaceutical formulation for use in a metered dose aerosol inhaler, comprising an active ingredient consisting of an anticholinergic quaternary ammonium salt in solution in a mixture consisting of a hydrofluoroalkane propellant, a cosolvent and a low volatility component, wherein the concentration of the active in gredient ranges from 0.11% to 1.14% by weight and the single dose delivered on actuation ranges from 60 to 640 μg.
Dependencies are inferred from the claim text.