Methods for the inhibition of exoprotein production from Gram positive bacteria

A method of inhibiting the production of exoprotein from Gram positive bacteria comprising exposing said Gram positive bacteria to an effective amount of a first active ingredient and a second active ingredient, said first active ingredient comprising an isoprenoid compound and said second active ingredient having the general formula:

• 7
• wherein R10 is a straight or branched alkyl or straight or branched alkenyl having from 8 to about 18 carbon atoms and R11 is selected from the group consisting of an alcohol, a polyalkoxylated sulfate salt and a polyalkoxylated sulfosuccinate salt.

A method of inhibiting the production of exoprotein from Gram positive bacteria comprising exposing said Gram positive bacteria to an effective amount of a first active ingredient and a second active ingredient, said first active ingredient comprising an isoprenoid compound and said second active ingredient having the general formula:

• 8
• wherein Z is a saccharide residue having 5 or 6 carbon atoms, n is a whole number from 1 to 6, and R14 is a linear alkyl group having from about 8 to about 18 carbon atoms.

A method of inhibiting the production of exoprotein from Gram positive bacteria comprising exposing said Gram positive bacteria to an effective amount of a first active ingredient and a second active ingredient, said first active ingredient comprising an isoprenoid compound and said second active ingredient having the general formula:

• 9
• wherein R1, inclusive of the carbonyl carbon, is an alkyl group having 8 to 18 carbon atoms and R2 and R3 can be the same or different. Preferably, R2 and R3 are selected from hydrogen and an alkyl group having 1 to about 12 carbon atoms. The alkyl group of R2 and R3 may contain one or more substituent groups selected from ester, ether, amine, hydroxyl, carboxyl, carboxyl salts, sulfonate and sulfonate salts.

A method of inhibiting the production of exoprotein from Gram positive bacteria comprising exposing said Gram positive bacteria to an effective amount of a first active ingredient and a second active ingredient, said first active ingredient comprising an isoprenoid compound and said second active ingredient having the general formula:

• 10
• wherein R1 is an alkyl group having from about 8 to about 18 carbon atoms and R2 and R3 can be the same or different and are selected from hydrogen and alkyl groups having from 1 to about 18 carbon atoms.