Use of particular compounds for prophylaxis and treatment of hepatitis c
OwnerLutz Webber, Sven Nerdinger +2inventors
InventorsLutz Webber, Sven Nerdinger, Michael W Cappi, Dirk Behnke
Life of this patent
Estimating the term…
Abstract
The present invention relates to the use of a compound of formula (I): 1 wherein: U—V—W(R1)—X(R2)—Y—Z has the formula RHN—C═CR1—CR2═C—OH, HO—C═CR1—CR2═C—OH or O═C—CR1═CR2—C═O, A is an N atom or the group CH, R is an H atom, a C1-C6alkyl group or a benzyl group, R1 is an H atom or a methyl group, and R2 is an H atom or a group of formula 2 for therapy or prophylaxis of hepatitis C.
Claims13
Use of a compound of formula (I):
- 16
- wherein:
- U—V—W(R1)—X(R2)—Y—Z has the formula RHN—C═CR1—CR2═C—OH, HO-C═CR1—CR2═C—OH or O═C—CR1═CR2—C═O,
- A is an N atom or the group CH,
- R is an H atom, a C1-C6alkyl group or a benzyl group,
- R1 is an H atom or a methyl group, and
- R2 is an H atom or a group of formula
- 17
- n being 6,7, 8 or 9,
- for therapy or prophylaxis of hepatitis C.
Use according to one of the preceding claims, characterised in that A is a CH group:
- 21
Use according to one of the preceding claims, characterised in that R is an H atom.
Use according to one of the preceding claims, characterised in that the compound has the formula:
- 23
Use according to one of the preceding claims, characterised in that the compound is administered orally, parenterally, transdermally, intranasally, transmucosally, systemically, subcutaneously, intravascularly, intramuscularly, topically, rectally or intravaginally.
Use according to one of the preceding claims, characterised in that the compound is formulated as a capsule, tablet, pastille, lozenge, spray, nasal spray, pessary, suppository, injection preparation, enema, ointment, cream or patch.
Use according to one of the preceding claims, characterised in that the compound is formulated as a delayed-release preparation.
Use according to one of the preceding claims, characterised in that, in addition, a further active ingredient is used.
Dependencies are inferred from the claim text.