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OwnerRobert Dudley, Shutsung Liao +1inventors
InventorsRobert Dudley, Shutsung Liao, Ching Song
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Compositions, methods, combinations, and kits for treating a disorder related to elevated serum cholesterol concentration, for example, atherosclerosis, elevated LDL plasma levels, low HDL plasma levels, hypertriglyceridemia, hyperlipidemia, hypertension, hypercholesterolemia, cholesterol gallstones, lipid storage diseases, obesity, and diabetes. The compositions, methods, combinations, and kits of the present invention are pharmaceutical compositions comprising at least two of an LXR receptor modulator, a therapeutically effective amount of a catechin, and/or a therapeutically effective amount of a lipid regulating agent, such as a HMG-CoA reductase inhibitor, a fibric acid derivative, niacin, a bile-acid sequestrant, an absorption inhibitor, probucol, raloxifene and its derivatives, an azetidinone compound, and an unsaturated omega-3 fatty acid.
A pharmaceutical composition, comprising:
A pharmaceutical composition, comprising:
A kit for treating a disorder related to elevated serum cholesterol concentration in a mammalian subject, comprising:
A kit for treating a disorder related to elevated serum cholesterol concentration in a mammalian subject, comprising:
A method for treating a disorder related to elevated serum cholesterol concentration in a mammalian subject, comprising administering to the subject a therapeutically effective amount of a LXR receptor modulator that is an oxysterol in combination with a therapeutically effective amount of a lipid regulating agent selected from the group consisting of a HMG-CoA reductase inhibitor, a fibric acid derivative, niacin, a bile-acid sequestrant, ezetimibe, probucol, raloxifene and its derivatives, and an unsaturated omega-3 fatty acid.
A method for treating a disorder related to elevated serum cholesterol concentration in a mammalian subject, comprising administering to the subject a therapeutically effective amount of a LXR receptor modulator in combination with a therapeutically effective amount of a catechin.
Dependencies are inferred from the claim text.