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US 2003/0153527 A1Published application
Method for introducing and expressing genes in animal cells, and live invasive bacterial vectors for use in the same
AssigneeUniversity of Maryland
InventorsRobert J. Powell, George K. Lewis, David M. Hone
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Abstract
A method for introducing and expressing genes in animal cells is disclosed comprising infecting said animal cells with live invasive bacteria, wherein said bacteria contain a eukaryotic expression cassette encoding said gene. The gene may encode, e.g., a vaccine antigen, an therapeutic agent, an immunoregulatory agent or a anti-sense RNA or a catalytic RNA.
Claims20
A method for introducing and expressing a gene in animal cells comprising infecting said animal cells with live invasive bacteria, wherein said bacteria contain a eukaryotic expression cassette encoding said gene.
Dependencies are inferred from the claim text.