Nucleic acid treatment of diseases or conditions related to levels of Ras
OwnerJames McSwiggeninventor
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Abstract
The present invention relates to nucleic acid molecules, including enzymatic nucleic acid molecules, such as DNAzymes (e.g. DNA enzymes, catalytic DNA), that modulate the expression of Ras genes such as K-Ras, H-Ras, and/or N-Ras.
Claims67
A siRNA nucleic acid molecule that modulates expression of a nucleic acid molecule encoding K-Ras.
A siRNA nucleic acid molecule that modulates expression of a nucleic acid molecule encoding H-Ras or N-Ras.
An enzymatic nucleic acid molecule that modulates expression of a sequence encoding K-Ras.
An enzymatic nucleic acid molecule that modulates expression of a sequence encoding H-Ras or N-Ras.
An enzymatic nucleic acid molecule comprising a sequence of SEQ ID NOs:
- 1322-2642 or 3650-4655.
An enzymatic nucleic acid molecule comprising at least one binding arm wherein one or more of said binding arms comprises a sequence complementary to a sequence of SEQ ID NOs:
- 1-1321 or 2643-3649.
A siRNA nucleic acid molecule comprising a sequence complementary to a sequence of SEQ ID NOs:
- 1-1321 or 2643-3649.
Dependencies are inferred from the claim text.