Remedies for cancer
OwnerAkikuni Yagitainventor
Life of this patent
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Abstract
There is provided a therapeutic agent for cancer mainly comprising a saccharide having an α1→3 steric structure where an action of NKT cells on NKR-P1 (natural killer receptor P1) which is a natural killer (NK) cell antigen receptor of NKT cells in an activating ability of natural killer T (NKT) is used as an index and being used in a formulation where the activation can be sustained.
Claims17
(amended) A composition where a saccharide having an α1→3 steric structure is a main ingredient in which activation of natural killer (NK) cell antigen receptor NKR-P1 (natural killer receptor P1) of human natural killer T (NKT) cells is monitored so that an effective dose by oral administration to cancer is formulated.
(amended) A method for the therapy of cancer by a composition where a saccharide having an α1→3 steric structure is a main ingredient in which activation of NKR-P1 is monitored by the measurement of CD 3 and CD 161 as an index for the activating action to NKR-P1 (natural killer receptor P1) of human NKT cells so that an effective dose by oral administration to cancer is formulated.
(amended) A supplementary food preparation for health by oral administration containing composition that a saccharide having an α1→3 steric structure as a main ingredient, where activation of NKR-P1 is monitored by the measurement of CD 3 and CD 161, as an index for activation to natural killer (NK) cell antigen receptor NKR-P1 (natural killer receptor P1) of human natural killer T (NKT) cells so that effective dose to cancer is taken.
(cancelled)
(amended) A screening method for therapeutic agent for cancer by oral administration where a saccharide having an α1→3 steric structure is a main ingredient, characterized in that, the screening is carried out using an action of NKT cells on NKR-P1 (natural killer receptor P1), which is a natural killer (NK) cell antigen receptor of NKT cells in an activating ability of human natural killer T (NKT) is used, as an index.
A screening method for therapeutic agent for cancer where a saccharide having an α1→3 steric structure is a main ingredient, characterized in that, the screening is carried out using an action of NKT cells on NKR-P1 (natural killer receptor P1), which is a natural killer (NK) cell antigen receptor of NKT cells in an activation of natural killer T (NKT), as an index, wherein activation of the said NKT cell is tested by measuring the NKR-P1 (natural killer receptor P1) by the measurement of CD 3 and CD 161 which are cell surface markers.
(amended) A testing means for judging the usefulness of a composition where a saccharide having an α1→3 steric structure is a main ingredient, characterized in that, the test is carried out using an action of NKT cells on NKR-P1 (natural killer receptor P1), which is a natural killer (NK) cell antigen receptor of NKT cells in an activating ability of human natural killer T (NKT), as an index.
(amended) A testing means for judging the usefulness of a composition where a saccharide having an α1→3 steric structure is a main ingredient, characterized in that, the test is carried out using an action of NKT cells on NKR-P1 (natural killer receptor P1), which is a natural killer (NK) cell antigen receptor of NKT cells in an activating ability of human natural killer T (NKT), as an index, wherein activating ability of the said human NKT cell is tested by measuring the NKR-P1 (natural killer receptor P1) by the measurement of CD 3 and CD 161 which are cell surface markers.
Dependencies are inferred from the claim text.