Curcumin derivatives with improved water solubility compared to curcumin and medicaments containing the same
OwnerManfred Hergenhahn, Barbara Bertram +2inventors
InventorsManfred Hergenhahn, Barbara Bertram, Manfred Wiessler, Bernda L Sorg
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Abstract
The invention relates to curcumin derivatives with improved water solubility compared to curcumin, which are characterized in that the curcumin part is linked to a monosaccharide, oligosaccharide or polysaccharide, and to medicaments containing these derivatives. The curcumin derivatives according to the invention are particularly suitable to prevent and treat cancer, chronic-inflammatory diseases and diseases associated with a retrovirus infection.
Claims12
Curcumin derivatives having a water solubility improved as compared to curcumin, characterized in that the curcumin part is linked to one or several saccharide portions, the saccharide being no glucuronic acid.
A medicament containing curcumin derivatives having a water solubility improved as compared to curcumin, wherein the curcumin part is linked to one or several saccharide portions.
Use of a curcumin derivative having a water solubility improved as compared to curcumin, wherein the curcumin part is linked to one or several saccharide portions, for the prevention or treatment of cancer.
Use of a curcumin derivative having a water solubility improved as compared to curcumin, wherein the curcumin part is linked to one or several saccharide portions, for the prevention or treatment of EBV-, HBV- or HPV-associated tumors or transplantation-associated lymphoproliferative diseases.
Use of a curcumin derivative having a water solubility improved as compared to curcumin, wherein the curcumin part is linked to one or several saccharide portions, for treating chronic-inflammatory diseases.
Use of a curcumin derivative having a water solubility improved as compared to curcumin, wherein the curcumin part is linked to one or several saccharide portions, for treating diseases associated with a retrovirus infection.
Dependencies are inferred from the claim text.