Screening crystallization conditions of organic compounds
OwnerMaxim Emile Kuil, Philippus Jacobus Hoedemaeker +3inventors
InventorsMaxim Emile Kuil, Philippus Jacobus Hoedemaeker, Jan Pieter Abrahams, Ian Ernest Maxwell, Jasper Rikkert Plaisier
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Abstract
A method for identifying crystallization conditions for at least one analyte, including providing a set of compositions, each composition comprising at least one analyte, and inducing or allowing each composition to adopt at least a first condition possibly influencing crystallization and detecting any crystallization in at least one composition.
Claims33
A method for detecting polymorphism of at least one analyte, said mehthod comprising:
- providing a set of compositions, each said composition comprising at least one analyte,
- inducing or allowing each composition to adopt at least a first condition possibly influencing crystallization, and
- detecting any crystallization in at least one composition.
A method for screening the polymorphic behavior of at least one analyte, said method comprising:
- providing a solid support medium comprising of a multitude of separate cells;
- providing two or more of the separate cells with the at least one analyte and other components such that the total composition of an individual cell differs in at least one aspect from the composition of at least one other cell;
- and
- detecting changes in polymorphic behavior of the compositions in the separate cells by determining the crystal form of the analyte.
Crystalline material produced by a method of any one of the previous method claims.
Dependencies are inferred from the claim text.