Method for extending the useful shelf-life of refrigerated red blood cells by nutrient supplementation
OwnerMark W. Bitensky, Tatsuro Yoshidainventors
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Abstract
There is provided methods and compositions for the storage of red blood cells. The compositions are metabolic supplements which are preferably added to refrigerated red blood cells suspended in an additive solution. Red blood cells are preferably stored under conditions of oxygen-depletion. Metabolic compositions comprises pyruvate, inosine, adenine, and optionally dibasic sodium phosphate and/or monobasic sodium phosphate.
Claims14
A method for the storage of red blood cells comprising:
- adding a metabolic supplement at least once to red blood cells;
- and
- storing said red blood cell under refrigeration.
A method for extending the storage life of refrigerated packed red blood cells which comprises adding a metabolic supplement to said refrigerated packed red blood cells.
A method for extending the storage life of refrigerated red blood cells comprising:
- adding a first solution to packed red blood cells;
- storing said red blood cells in oxygen-depleted refrigeration;
- and
- adding a second solution to said red blood cells.
Dependencies are inferred from the claim text.