Novel g protein-coupled receptor protein and dna thereof
OwnerTakeo Moriya, Takashi Ito +2inventors
InventorsTakeo Moriya, Takashi Ito, Yasushi Shintani, Hideki Matsui
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Abstract
A novel G protein-conjugating receptor protein containing an amino acid sequence which is the same or substantially the same as the amino acid sequence represented by SEQ ID NO.1, or its salt; a polynucleotide encoding the same; and medicinal use, etc. thereof.
Claims36
A G protein-conjugating receptor protein comprising an amino acid sequence identical or substantially identical to the amino acid sequence represented by SEQ ID NO.1, or a salt thereof.
10 The antibody according to claim 9 which is a neutralizing antibody which inactivates the signal transmission of the G protein-conjugating receptor protein according to claim 1.
17 A compound or a salt thereof capable of altering the binding affinity between a ligand and the G protein-conjugating receptor protein according to claim 1 or a salt thereof, which is obtainable by using the screening method according to claim 15 or a screening kit according to claim 16.
Dependencies are inferred from the claim text.