Scintillation proximity test
AssigneeGe Healthcare Limited
InventorRobert A. Jessop
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Abstract
The invention concerns scintillation proximity assays performed in multiwell plates where a charge coupled device is used to image the wells. Conventional phosphors emit blue light (350-450 nm) which is absorbed by yellow or brown assay components. This problem is addressed by the use of phosphors that emit radiation of longer wavelength (480-900 nm).
Claims10
Use in a scintillation proximity test of a phosphor that has an emission maximum of 480 nm-900 nm, and of a charge coupled device for detecting radiation emitted by the phosphor.
A method of performing a scintillation proximity test, by providing a solid surface comprising a phosphor in a fluid medium, causing a radiolabelled reagent to become divided into two fractions one bound to the solid surface and the other in the fluid medium, and detecting the fraction of the radiolabelled reagent bound to the solid surface,
- characterised by using a phosphor that has an emission maximum of 480 nm-900 nm and a charge coupled device for detecting radiation emitted by the phosphor.
Dependencies are inferred from the claim text.