Polyfunctional support material for complex nucleic acid analysis
OwnerPeter Bendzko, Uwe Schedler +2inventors
InventorsPeter Bendzko, Uwe Schedler, Heike Matuschewski, Timo Hillebrand
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Abstract
The invention relates to a material for the complex manipulation of nucleic acids as a platform technology for developing integrative, fully automatic systems for nucleic acid analysis. The inventive support material for complex nucleic acid analysis is characterised in that at least one covalently bonded layer is located on the surface, said layer bearing at least two different functional groups which are statistically distributed on the surface. At least one of the functional groups is negatively charged and at least one other functional group is positively charged or chemically reactive or has both of these properties.
Claims36
Support material for complex nucleic acid analysis, characterized in that at least one covalently bonded layer is found on the surface that carries at least two different functional groups and that is statistically dispersed on the surface, whereby
- at least one of the functional groups is negatively charged,
- at least one other functional group is positively charged or chemically reactive or has both properties.
Process for complex and automatable analysis of biological materials, especially nucleic acids, wherein the necessary preparation and analysis steps, especially the extraction, binding, manipulation and detection of the nucleic acids are performed simultaneously or in succession on the same support material.
Dependencies are inferred from the claim text.