Phosphatases
OwnerOlga Bandman, Y. Tom Tang +9inventors
InventorsOlga Bandman, Y. Tom Tang, Yalda Azimzai, Henry Yue, Mariah R. Baughn, Jennifer L. Hillman, Preeti Lal, Eureka Wang, Ameena R. Gandhi, Jennifer L. Policky, Preete Mathur
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Abstract
The invention provides human phosphatases (PP) and polynucleotides which identify and encode PP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PP.
Claims62
An isolated polypeptide comprising an amino acid sequence selected from the group consisting of:
- a) an amino acid sequence selected from the group consisting of SEQ ID NO:1-9,
- b) a naturally occurring amino acid sequence having at least 90% sequence identity to an amino acid sequence selected from the group consisting of SEQ ID NO:1-9,
- c) a biologically active fragment of an amino acid sequence selected from the group consisting of SEQ D) NO:1-9, and
- d) an immunogenic fragment of an amino acid sequence selected from the group consisting of SEQ ID NO:1-9.
An isolated polynucleotide comprising a polynucleotide sequence selected from the group consisting of:
- a) a polynucleotide sequence selected from the group consisting of SEQ ID NO:10-18,
- b) a naturally occurring polynucleotide sequence having at least 90% sequence identity to a polynucleotide sequence selected from the group consisting of SEQ ID NO:10-18,
- c) a polynucleotide sequence complementary to a),
- d) a polynucleotide sequence complementary to b), and
- e) an RNA equivalent of a)-d).
Dependencies are inferred from the claim text.