Novel secreted proteins and polynucleotides encoding them

An isolated polypeptide selected from the group consisting of:

• a) a polypeptide at least 80% homologous to any one of the amino acid sequences of SEQ ID NO:
• 2, 4 and 6;
• b) a polypeptide at least 80% homologous to the amino acid sequence of SEQ ID NO:
• 8;
• c) a polypeptide at least 60% homologous to any one of the amino acid sequences of SEQ ID NO:
• 10 and 12;
• d) a polypeptide at least 80% homologous to any one of the amino acid sequences of SEQ ID NO:
• 15 and 17;
• e) a fragment of a polypeptide comprising any one of the amino acid sequences of SEQ ID NOs:
• 2, 4, 6, 8, 10, 12, 15 and 17, wherein the fragment comprises at least 6 amino acids of any one of SEQ ID NOs:
• 2, 4, 6, 8, 10, 12, 15 and 17;
• and
• f) a naturally occurring allelic variant consisting of any one of the amino acid sequence of SEQ ID NOs:
• 2, 4, 6, 8, 10, 12, 15 and 17, wherein the polypeptide is encoded by a nucleic acid molecule that hybridizes under stringent conditions to a nucleic acid molecule consisting of any one of SEQ ID NOs:
• 1, 3, 5, 7, 9, 11, 13, 14 and 16.

A method of detecting the presence of a nucleic acid molecule having a sequence at least 80% identical to a nucleic acid comprising a sequence selected from the group consisting of SEQ ID NOs:

• 1, 3, 5, 7, 9, 11, 13, 14 and 16, or a complement thereof, in a sample from a mammal, the method comprising:
• a) contacting the sample with a nucleic acid probe or primer which selectively hybridizes to the nucleic acid molecule;
• and
• b) determining whether the nucleic acid probe or primer binds to a nucleic acid molecule in the sample,
• wherein binding of the nucleic acid probe or primer indicates the nucleic acid molecule is present in the sample.