Method of screening a gene
AssigneeNihon University, School Juridical Person
InventorsSatoshi Asai, Toshihito Nagata, Yasuo Takahashi, Yukimoto Ishii, Koichi Ishikawa
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Abstract
The present invention provides a method of screening genes based on expression information differing from gene expression information obtainable by DNA chip/DNA microarray techniques. The method of screening genes comprises performing in situ hybridization in respect of a tissue or cell sample from an organism using a probe which specifically hybridizes with mRNA and/or expression sequence tag being a product of gene expression, and examining localization of the mRNA and/or expression sequence tag in the tissue or cell.
Claims12
A method of screening genes which comprises performing in situ hybridization of a tissue or cell sample of an organism, using a probe which hybridizes specifically with mRNA and/or an expression sequence tag being a product of gene expression, and examining the localization of the mRNA and/or expression sequence tag in the tissue or cell.
A method of monitoring gene expression which comprises collecting a tissue or cell sample from an organism each before occurrence, and after occurrence of an event, performing in situ hybridization in respect of each sample using a probe that specifically hybridizes with mRNA and/or an expression sequence tag being a product of gene expression, and examining changes in localization of the mRNA and/or expression sequence tag in the tissue or cell.
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