Novel methods of diagnosis of angiogenesis, compositions and methods of screening for angiogenesis modulators
AssigneeEos Biotechnology, Inc.
InventorsRichard Murray, Richard Glynne, Susan R. Watson
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Abstract
Described herein are methods and compositions that can be used for diagnosis and treatment of angiogenic phenotypes and angiogenesis-associated diseases. Also described herein are methods that can be used to identify modulators of angiogenesis.
Claims29
A method of detecting an angiogenesis-associated transcript in a cell in a patient, the method comprising contacting a biological sample from the patient with a polynucleotide that selectively hybridized to a sequence at least 80% identical to a sequence as shown in Table 1.
An isolated nucleic acid molecule consisting of a polynucleotide sequence as shown in Table 1.
An isolated nucleic acid molecule which encodes a polypeptide having an amino acid sequence as shown in Table 2.
An isolated polypeptide which is encoded by a nucleic acid molecule having polynucleotide sequence as shown in Table 1.
An isolated polypeptide having an amino acid sequence as shown in Table 2.
The method of detecting antibodies specific to angiogenesis in a patient, the method comprising contacting a biological sample from the patient with a polypeptide comprising a sequence as shown in Table 2.
Dependencies are inferred from the claim text.