US 2003/0152639 A1 · Novel wound healing composition not containing bovine-derived activating reagents

Abstract

A wound care preparation free from bovine-derived activating agents is disclosed for use in wound care, for both topical wounds and surgical wounds. The preparation is isolated by first obtaining an amount of whole blood from the patient and treating the whole blood with one or more anti-clotting agents, subjecting the whole blood to a centrifugation process to obtain an amount of platelet-rich plasma, adding to the platelet-rich plasma an amount of anti-clotting neutralizing agent, and mixing the platelet-rich plasma with a structural matrix to increase viscosity of the preparation. In use, the viscous preparation can be applied directly to a wound or surgery incision and the viscous preparation may be mixed with other wound healing agents, growth matrices, or promoters such as anti-fungal agents, anti-biotic agents, and preservatives.

Claims11

Dependent claims

A preparation for use in treating damaged tissue, the isolation thereof comprising the steps of:

(a) isolating from the patient an amount of whole blood, treating said whole blood with an anti-coagulant agent, and subjecting said whole blood to a centrifugation process to obtain an amount of platelet-rich plasma;
(b) adding to the platelet-rich plasma an effective amount of anticoagulant neutralizing agent and fibrinolysis inhibitor;
and
(c) suspending the platelet-rich plasma by mixing it with one or more structural matrices from a group consisting of maltodextrin powder, hydroxyethyl cellulose, calcium alginate, carageenan, hydroxyethyl starch, hyaluronic acid, regenerated oxidized cellulose, methyl cellulose, and/or glycerin, to increase viscosity of the platelet-rich plasma and to form a gelatinous preparation;
and,
(d) subsequently storing said gelatinous preparation in an unactivated state.

3 more elements

Dependencies are inferred from the claim text.

Novel wound healing composition not containing bovine-derived activating reagents

Life of this patent

Novel wound healing composition not containing bovine-derived activating reagents

Life of this patent

Abstract

Claims11