Pharmaceutical compositions for transdermal administration of anti-inflammatory agents

Pharmaceutical composition for transdermal administration, characterized in that it comprises, by weight:

• a) from 0.5% to 2% of a polymeric release matrix capable of forming a supple film after drying, chosen from cellulosic polymers or copolymers
• b) from 3% to 10% of an active principle chosen from the group of nonsteroidal anti-inflammatory agents containing at least one carboxylic or metal carboxylate group
• c) from 10% to 30% of a promoter of transcutaneous absorption of the active principle chosen from:
• 2-ethylhexyl 2-ethylhexanoate
• isopropyl myristate
• diethylene glycol monoethyl ether myristate
• isopropyl palmitate
• 2-octyldodecanol
• 2-ethylhexyl undecylenate
• 2-ethylhexyl succinate
• 2-ethylhexyl 12-hydroxystearate
• hexyl laurate
• glyceryl isostearate
• 2-ethylhexyl 12-acetoxystearate
• d) from 3% to 10% of water
• e) a sufficient amount, to reach 100% of the weight of the composition, of at least one physiologically acceptable nonaqueous solvent capable of dissolving the release matrix, the active principle and the transcutaneous absorption promoter, and also of being rapidly eliminated by evaporation on contact with the skin, chosen from dichloromethane, ethanol, isopropanol or ethyl acetate.