Delivery device
AssigneeMW Encap Limited
InventorsMassoud Bakhshaee, William John Bowtle, Alyn Brandon McNaughton
Life of this patent
Estimating the term…
Abstract
An active principle delivery device (1) comprising an inner capsule (4) within an outer capsule (2), the inner and outer capsules (4, 2) containing the same active principle (5, 3), with at least the outer capsule (2) being a hard capsule and the active principle (3, 5) in at least one of the capsules (2, 4), comprising a fluid. Also provided is a method of fabricating such a delivery device (1), as well as a method of controlling the pharmaco-kinetic profile of an active principle.
Claims33
An active principle delivery device comprising an inner capsule within an outer capsule, wherein:
- the inner and outer capsules contain the same active principle;
- at least the outer capsule is a hard capsule;
- and
- the active principle in at least one of the capsules comprises a fluid (as hereinbefore defined)
A delivery device according to any preceding claim, wherein the active principle comprises a fluid suspended solid.
A delivery device according to any preceding claim, wherein at least one of the inner and outer capsules contains the active principle in more than one phase.
A delivery device according to any preceding claim comprising more than one inner capsule within the outer hard capsule, the inner capsules being arranged in parallel and/or in series.
A delivery device according to any preceding claim which provides a pharmaceutical dosage form for the administration of the same active principle in single therapies.
A delivery device according to any preceding claim, wherein the active principle comprises a medicinal or nutritional product.
A delivery device according to any preceding claim further comprises an activator or co-reactant for the active principle.
A method of fabricating an active principle delivery device, comprising:
- providing a first capsule and a second capsule of which at least the first capsule is a hard capsule;
- placing the same active principle in each of the first and second capsules, with the active principle in at least one of the capsules comprising a fluid (as hereinbefore defined);
- and
- placing the second, active principle-containing capsule within the first, active principle-containing, hard capsule.
A method of controlling the pharmaco-kinetic profile of an active principle comprising the steps of:
- determining a first efficacious site for active principle release;
- placing an active principle in a first hard capsule;
- placing the same active principle in a second capsule within the active-principle-containing, first hard capsule, with the active principle in at least one of the first and second capsules comprising a fluid (as hereinbefore defined);
- delivering the delivery device to the predetermined site;
- and
- controlling the release of the active principle at the site.
Dependencies are inferred from the claim text.