Filtration unit comprising calendered leukocyte-removing layers
OwnerThierry Verpoort, Stephane Cholletinventors
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OwnerThierry Verpoort, Stephane Cholletinventors
Estimating the term…
The present invention is directed to a filtration unit intended to allow the removal of leukocytes from a fluid such as blood or a blood component. The filtration unit contains a porous element comprising a medium for the removal of leukocytes by adsorption and filtration of the leukocytes. The medium comprises a number of layers of a first type which are formed from at least one porous non-woven material. At least one layer has been pressed by calendering prior to the stacking thereof. The at least one calendered layer is disposed on the downstream side of the stack. The medium also comprises at least one non-calendered layer. The present invention is also directed to a bag-based system comprising the filtration unit. The system is in particular arranged for the sterile and closed-circuit filtration of the fluid.
A filtration unit for removing leukocytes from a fluid such as blood or a blood component, said filtration unit comprising an outer casing provided with at least one input aperture and at least one output aperture between which the fluid to be filtered flows in one direction, said outer casing comprising a porous element comprising a medium for the removal of leukocytes by adsorption and filtration of the leukocytes, said medium comprising a plurality of stacked layers having an upstream side and a downstream side of a first type which are formed from at least one porous non-woven material, wherein at least one layer has been pressed by calendering prior to the stacking thereof, said at least one calendered layer being disposed on the downstream side of the stack, the medium further comprising at least one non-calendered layer.
A bag-based system for the removal of leukocytes from a fluid such as blood or a blood component, comprising a bag for collecting filtrate, said bag being connected, by a tube and at an input aperture to an output aperture of a filtration unit, said filtration unit comprising an outer casing comprising a porous element comprising a medium for the removal of leukocytes by adsorption and filtration of the leukocytes, said medium comprising a plurality of stacked layers, having an upstream side and a downstream side, which are formed from at least one porous nonwoven material, wherein at least one layer has been pressed by calendering prior to stacking thereof, said at least one calendered layer being disposed on the downstream side of the stack, the medium further comprising at least one non-calendered layer.
An apparatus for removing leukocytes from blood or a blood component, comprising a porous element comprising, a leukocyte removing medium formed of a plurality of stacked layers, at least one of said plurality of stacked layers being calendered.
Dependencies are inferred from the claim text.