Gene associated with cancer
OwnerTakao Shinozawa, Kazi Mokim Ahmed +3inventors
InventorsTakao Shinozawa, Kazi Mokim Ahmed, Yoshinori Shitara, Hiroyuki Kuwano, Seiichi Takenoshita
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Abstract
A method of anticipating risk of the onset of cancer in an individual, including (1) obtaining a sample derived from the individual, (2) analyzing a polymorphism of a Midkine gene concerning the sample of (1), and (3) anticipating risk of the onset of cancer based on the polymorphism determined in (2) above.
Claims15
A method of anticipating risk of the onset of cancer in an individual, comprising:
- (1) obtaining a sample derived from the individual;
- (2) analyzing a polymorphism of a Midkine gene concerning the sample of (1);
- and
- (3) anticipating risk of the onset of cancer based on the polymorphism determined in (2) above.
A method of anticipating risk of the onset of cancer in an individual using a computer, the method comprising:
- (1) recording information of a genotype of a Midkine gene determined using a sample derived from the individual in data recording means;
- (2) directing risk of the onset of cancer based on the genotype recorded in (1) above, in accordance with a table which corresponds the risk of the onset of cancer with a genotype previously stored in the computer;
- and
- (3) outputting the anticipation result obtained in (2) above.
A method of anticipating risk of the onset of cancer in an individual using a computer, the method comprising:
- (1) inputting by an operator the genotype of the Midkine gene determined using the sample derived from the individual, into the computer;
- (2) directing by the computer risk of the onset of cancer in accordance with a table which corresponds the risk of the onset of cancer with a genotype previously stored in storage means of the computer, based on the genotype inputted in (1) above;
- and
- (3) showing by the computer the anticipation result obtained in (2) above to the operator.
A program for, to anticipate risk of the onset of cancer in an individual, making a computer function as:
- (1) means for recording information of a genotype of a Midkine gene determined using a sample derived from the individual;
- (2) means for directing risk of the onset of cancer based on the genotype recorded in (1) above, in accordance with a table which corresponds the risk of the onset of cancer with a genotype previously stored in the computer;
- and
- (3) means for outputting the anticipation result obtained in (2) above.
An anticipating device anticipating risk of the onset of cancer in an individual, comprising:
- (1) storage means for storing a table which corresponds a genotype with risk of the onset of cancer;
- (2) inputting means for inputting information of a genotype of MK808 determined using a sample derived from an individual which is a tested object;
- (3) anticipating means for inducing the risk of the onset of cancer, based on the genotype inputted through the inputting means and the table stored by the storage means;
- and
- (4) display means for displaying the anticipation result of the anticipation means.
A DNA micro array comprising at least one polynucleotide which is selected from a group consisting of the following polynucleotides, as a nucleic acid probe to determine a genotype of MK808:
- (a) a polynucleotide which is selected from SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3 and SEQ ID No. 4;
- (b) a modified polynucleotide in which one or more nucleotides excluding MK808 which is a gene associated with cancer are deleted, substituted or added, in the polynucleotides shown in (a) above;
- (c) a polynucleotide which is a partial fragment of a MK gene containing MK808 site;
- and
- (d) a complementary chain of the polynucleotides described in (a) to (d) above.
Dependencies are inferred from the claim text.