Methods of repairing longitudinal bone defects
AssigneeTcchnion Research & Development Foundation Ltd.
InventorsErella Livne, Samer Srouji
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Abstract
A method of repairing a long bone having a defect is provided. The method includes the steps of: (a) mechanically fixating the long bone or portions thereof; and (b) filling the defect with a biodegradable scaffold impregnated with growth factors and/or osteoprogenitor cells and awaiting for osteointegration to take place.
Claims127
A method of repairing a long bone selected from the group consisting of a femur, a tibia, a humerus and a radius having a defect, the method comprising:
- (a) using an external mechanical fixating device for mechanically fixating the long bone or portions thereof;
- and
- (b) filling the defect with a biodegradable cross-linked acidic gelatin designed to promote osteointegration and awaiting for osteointegration to take place.
A kit for repairing a long bone selected from the group consisting of a femur, a tibia, a humerus and a radius having a defect, the kit comprising:
- (a) an external mechanical fixating device for fixating the long bone or portions thereof;
- and
- (b) a filler for filling the defect, said filler including a biodegradable cross-linked acidic gelatin.
A method of repairing a long bone having a defect, the method comprising:
- (a) mechanically fixating the long bone or portions thereof;
- and
- (b) filling the defect with a biodegradable hydrogel containing osteoprogenitor cells and awaiting for osteointegration to take place.
A kit for repairing a long bone having a defect, the kit comprising:
- (a) a mechanical fixating device for fixating the long bone or portions thereof;
- and
- (b) a filler for filling the defect, said filler including a biodegradable hydrogel containing osteoprogenitor cells.
Dependencies are inferred from the claim text.