Bird diagnostics and treatments
OwnerVanessa Lopes, Kakambi V Nagarajainventors
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Abstract
The invention relates to methods and materials for protecting birds from infection with ORT as well as for detecting ORT infection in birds. Specifically, the invention provides ORT antigens, anti-ORT antibodies, and mutant ORT organism, as well as methods and materials for detecting and preventing ORT infections.
Claims67
A composition comprising an isolated mutant ORT organism.
A vaccine comprising an effective amount of a mutant ORT organism.
A method for protecting a bird from an ORT infection, said method comprising administering to said bird a composition comprising an effective amount of an isolated mutant ORT organism.
A method for reducing the risk of an ORT infection in a bird, comprising administering to said bird a composition comprising an isolated mutant ORT organism.
An inoculated bird, wherein said bird comprises anti-ORT antibodies due to inoculation with an isolated mutant ORT organism.
A method for identifying a bird that is or was infected with ORT, said method comprising:
- a) contacting a biological sample from said bird with an ORT antigen under conditions wherein said ORT antigen specifically binds to an anti-ORT antibody, if present in said biological sample, to form an antibody-antigen complex;
- and
- b) detecting the presence or absence of said antibody-antigen complex, the presence of said antibody-antigen complex indicating that said bird is or was infected with ORT.
A method for detecting an ORT infection in a bird, said method comprising:
- a) contacting a biological sample from said bird with an anti-ORT antibody under conditions wherein said anti-ORT antibody specifically binds to an ORT antigen, if present in said biological sample, to form an antibody-antigen complex;
- and
- b) determining the presence or absence of said antibody-antigen complex, the presence of said antibody-antigen complex indicating that said bird has said infection.
A composition comprising a substantially pure ORT antigen.
A composition consisting essentially of an ORT OMP preparation.
A composition comprising an ORT antigen and an indicator molecule.
A composition comprising an anti-ORT antibody and an indicator molecule.
Dependencies are inferred from the claim text.