Solid matrices for surface-enhanced raman spectroscopy
AssigneeAvalon Instruments Limited
InventorSteven Ernest John Bell
Life of this patent
Estimating the term…
Abstract
A method of forming a solid matrix for use with surface-enhanced Raman spectroscopy is described. The method comprises the steps of: admixing a colloidal metal solution with a polymeric support medium to form a suspension; optionally depositing said suspension on a surface; and then drying the suspension to form the matrix. The polymeric support medium provides a plymer/sol suspension in which the sol particles are resistant to aggregation and precipitation. Upon drying the suspension shrinks to provide a mechanically-hard film subsequently usable to provide a sample for spectroscopic analysis.
Claims32
A method of forming a solid matrix for use with surface-enhanced Raman spectroscopy, comprising the steps of:
- admixing a colloidal metal solution with a polymeric support medium to form a suspension;
- and
- drying the suspension to form the matrix.
A method as claimed in claim 11 wherein the cellulose-based substance is hydroxyethylcellulose.
A method as claimed in any one of the preceding claims wherein the metal in the metal solution is silver or gold.
A method as claimed in any one of the preceding claims wherein the solid matrix is subsequently powdered.
A solid matrix for use with surface-enhanced Raman spectroscopy, which matrix includes metal particles and a polymeric support medium.
The use of a solid matrix as defined in any one of the preceding claims in the preparation of a sample for analysis by surface-enhanced Raman spectroscopy.
Dependencies are inferred from the claim text.