Tocopherol derivatives
AssigneeSonus Pharmaceuticals, Inc.
InventorsYuehua Zhang, Manjari Lal, Nagesh Palepu
Life of this patent
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Abstract
Tocopherol derivatives are provided. In one embodiment, the tocopherol derivative includes a tocopherol moiety covalently coupled to branched hydrophilic moiety. In another embodiment, the tocopherol derivative includes a first tocopherol moiety covalently coupled to a second tocopherol moiety through a hydrophilic moiety. In other embodiments, the derivative includes three or more tocopherol moieties.
Claims64
A compound, comprising a first tocopherol moiety covalently coupled to a second tocopherol moiety through a hydrophilic moiety.
A compound having the structure:
- (E-L)nC
- wherein E comprises a tocopherol moiety
- wherein L comprises a hydrophilic moiety;
- wherein C comprises a core moiety;
- and
- wherein n=2-4.
A compound having the structure:
- 5
- wherein E comprises a tocopherol moiety;
- and
- wherein L comprises a hydrophilic moiety.
A compound having the structure:
- 6
- wherein E comprises a tocopherol moiety;
- and
- wherein L comprises a hydrophilic moiety.
A compound, comprising a tocopherol moiety covalently coupled to a branched hydrophilic moiety.
A compound having the structure:
- E-L-C(L)n
- wherein E comprises a tocopherol moiety
- wherein L comprises a hydrophilic moiety;
- wherein C comprises a core moiety;
- and
- wherein n=2 or 3.
A compound having the structure:
- 7
- wherein E comprises a tocopherol moiety;
- and
- wherein L comprises a hydrophilic moiety.
A compound having the structure:
- 8
- wherein E comprises a tocopherol moiety;
- and
- wherein L comprises a hydrophilic moiety.
Dependencies are inferred from the claim text.