Compositions for the treatment of infectious diseases
OwnerKurt R. Gehlsen, Kristoffer Hellstrandinventors
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Abstract
Described herein are compositions and methods for the treatment of microbial infection.
Claims20
A method for inhibiting and reducing enzymatically produced ROM-mediated oxidative damage to a patient's skin or mucosal membranes comprising the step of topically delivering an effective dose of a ROM production and release inhibitory compound in a pharmaceutically acceptable carrier to a subject suffering from ROM-mediated oxidative damage to said patient's are of infection.
A method for making a composition for topically delivering a compound that inhibits the production and release of enzymatically produced ROMs comprising:
- providing a pharmaceutically acceptable carrier and histamine in a concentration effective to treat a ROM mediated damage to skin caused by a microbial infection;
- and
- forming a composition containing the pharmaceutically acceptable carrier and said compound that inhibits the production and release of enzymatically produced ROMs.
A method for treating a microbial infection comprising the steps of:
- diagnosing a patient with a microbial infection;
- administering to that patient an effective amount of the appropriate chemotherapy;
- and
- administering to that patient a compound effective to inhibit the production or release of intracellular hydrogen peroxide selected form the group consisting of histamine, other H2 receptor agonists, and serotonin.
Dependencies are inferred from the claim text.