Bicyclic compounds as inhibitors of chemokine binding to US28

Abstract

Methods for treating CMV or a CMV-related disease are provided that use compounds having the formula: 1 wherein Ar is a substituted or unsubstituted 5-14 membered heteroaryl group having from 1 to 5 heteroatoms as ring members; R1 is selected from the group consisting of substituted or unsubstituted aryl(C1-C4)alkyl, heteroaryl(C1-C4)alkyl, —C(O)R11, and —C(O)NR11R12, wherein each R11 and R12 independently is substituted or unsubstituted aryl, substituted or unsubstituted aryl(C1-C4)alkyl, substituted or unsubstituted (C4-C8)cycloalkyl(C1-C4)alkyl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heteroaryl(C1-C4)alkyl and substituted or unsubstituted hetero(C4-C8)cycloalkyl(C1-C4)alkyl; R2 is H or (C1-C8)alkyl; and ZN is a substituted or unsubstituted hetero(C6-C10)bicycloalkyl group.

Dependencies are inferred from the claim text.