Combination of lipoic acid and c1 donors for the treatment of disorders of the central nervous system
OwnerWolfgang P Hahnlein, Klaus Kramer +3inventors
InventorsWolfgang P Hahnlein, Klaus Kramer, Oliver Hasselwander, Walter E Muller, Gunther P Eckert
Life of this patent
Estimating the term…
Abstract
The present invention relates to the use of lipoic acid and C1 donors, in particular S-adenosylmethionine and/or 5-methyltetrahydrofolate, for the treatment of central nervous system disorders, to compositions with a corresponding active ingredient combination and to compositions in the form of commercial packs with corresponding combination products or single component products for combined use.
Claims9
The use of at least one lipoic acid, of a physiologically acceptable derivative and/or salt thereof and at least one C1 donor for producing a composition for C1 donor-assisted treatment of central nervous system disorders.
The use as claimed in either of the preceding claims, where the C1 donor is involved in folate metabolism.
The use as claimed in any one of the preceding claims, where the C1 donor is selected from S-adenosylmethionine, 5-methyltetrahydrofolate, physiologically acceptable derivatives and/or salts thereof.
The use as claimed in any one of the preceding claims for the treatment of impairments of cognitive functions and of depression.
The use as claimed in any one of the preceding claims for the treatment of central nervous system disorders associated with aging.
A composition comprising
- i) at least one lipoic acid, a physiologically acceptable lipoic acid derivative and/or salt thereof, and
- ii) at least one C1 donor and,
- where appropriate, at least one other active ingredient and a formulation base.
A composition in the form of a commercial pack having at least one composition based on
- i) at least one lipoic acid, a physiologically acceptable lipoic acid derivative and/or salt thereof, and/or
- ii) at least one C1 donor,
- where appropriate with instructions for the therapeutic use of lipoic acid, lipoic acid derivatives or salts thereof in combination with at least one C1 donor.
Dependencies are inferred from the claim text.