Method and composition for inducing apoptosis in cells
OwnerHiremagalur Jayaram, Georg Krupitza +2inventors
InventorsHiremagalur Jayaram, Georg Krupitza, Thomas Szekeres, Michael Grusch
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Abstract
There is provided a composition including an ATP-inducing compound or ATP and an effective amount of cell death-inducing drug. Also provided is the method of inducing apoptosis in apoptosis-inducible cells by administering to the apoptosis inducible cells a composition including an effective amount of a cell death-inducing compound and an ATP-inducing compound or ATP. The present invention also provides a method of suppressing necrosis in cells by administering an effective amount of an ATP-inducing compound or ATP to a cell population, thereby inhibiting necrosis.
Claims21
A composition comprising an ATP-inducing compound and an effective amount of a cell death-inducing drug.
A composition comprising ATP or an ATP precursor and an effective amount of a cell death-inducing drug.
A method of inducing apoptosis in apoptosis-inducible cells by administering to the apoptosis-inducible cells a composition comprising a cell death-inducing effective amount of a cell death-inducing compound and an ATP-inducing compound.
A method of inducing apoptosis in apoptosis-inducible cells by administering to the apoptosis-inducible cells a composition comprising a cell death-inducing effective amount of a cell death-inducing compound and ATP.
A method of suppressing necrosis in cells by administering an effective amount of an ATP-inducing compound to a cell population exhibiting necrosis.
A composition for inducing apoptosis in apoptosis-inducible cells, said composition comprising an ATP-inducing compound and an effective amount of a cell death-inducing drug.
A composition for inducing apoptosis in apoptosis-inducible cells, said composition comprising ATP or an ATP precursor and an effective amount of a cell death-inducing drug.
Dependencies are inferred from the claim text.