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AssigneeHisamitsu Pharmaceutical Co., Inc.
InventorsTakeshi Goto, Keishi Yonemura, Tetsuji Kuwahara, Masanao Oya, Katsuhiko Akiyama
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A novel nucleic acid carrier and a pharmaceutical composition for gene therapy are disclosed. The nucleic acid carrier of this invention is characterized by containing a polypeptide comprising diaminobutyric acid with a suitable number of residues and/or a pharmaceutically acceptable salt thereof. The nucleic acid carrier of this invention can form a complex with a variety of therapeutic genes that is safe and has extremely low immunogenicity (the pharmaceutical composition of this invention); and it can allow the therapeutic gene to be introduced into cells efficiently and safely whereby high expression of the gene in the cells can be realized.
A nucleic acid carrier comprising a polypeptide comprising diaminobutyric acid and/or a pharmaceutically acceptable salt thereof.
A nucleic acid carrier comprising a block copolymer of a polypeptide comprising diaminobutyric acid and/or a pharmaceutically acceptable salt thereof and polyethylene glycol.
Dependencies are inferred from the claim text.