Insulin formulation for inhalation
OwnerJaap Kampingainventor
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Abstract
A particulate composition comprising particulates having a mixture of 10 to 40% insulin and 90 to 60% saccharide is shown to be particularly suited for pulmonary delivery to a patient.
Claims12
A particulate composition for pulmonary delivery, comprising particles having a mixture of 10 to 40% insulin and 90 to 60% of a saccharide.
A composition according to any preceding claim, wherein the mixture is 15 to 30% insulin and 85 to 70% saccharide.
A composition according to any preceding claim, wherein the mixture is 15 to 20% insulin and 85 to 80% saccharide.
A composition according to any preceding claim, wherein the mixture is about 20% insulin and about 80% saccharide.
A composition according to any preceding claim, wherein the saccharide is trehalose.
A composition according to any preceding claim, wherein the particles are 0.1 to 15 μm in size.
A composition according to any preceding claim, wherein the particles are in amorphous form.
A particulate composition for pulmonary delivery, comprising particles having a mixture of about 20% insulin and about 80% trahalose.
A device for the delivery of a therapeutic agent via the pulmonary route, comprising a composition according to any preceding claim.
Dependencies are inferred from the claim text.