Novel triazolo pyrimidine compounds

A process for preparing a compound of formula (II):

• 25
• comprising hydrogenating a compound of formula (IV):
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• wherein Ar is phenyl optionally substituted by halogen, C1-4 alkyl or C1-4 alkoxy.

The use of a compound of formula (I) to prepare a compound of formula (A):

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• comprising:
• (a) reacting a compound of formula (I) with an alkali metal nitrite in the presence of a suitable acid to prepare a compound of formula (VII):
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• (b) coupling the compound of formula (VII) with a compound of formula (VI):
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• to provide a compound of formula (V):
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• and,
• (c) deprotecting a compound of formula (V) to provide the compound of formula (A).

A process for preparing a salt of a compound of formula (III):

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• comprising the steps:
• (a) preparing a compound of formula (XI):
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• by reacting a compound of formula (XII):
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• with benzyl chloroformate;
• (b) preparing a compound of formula (X):
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• by reacting a compound of formula (XI) with a compound L-CH2CO2R* {wherein R* is C1-4 alkyl;
• and L is a leaving group};
• (c) preparing a compound of formula (IX):
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• by reducing a compound of formula (X);
• (d) preparing a compound of formula (III):
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• by deprotecting a compound of formula (IX);
• and,
• (e) preparing a salt of a compound of formula (III) by reacting the compound of formula (III) with the necessary acid.