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AssigneeThe Govt. of the U.S.A. as represented by the Secretary of the Dept. of Health & Human Services
InventorsMargaret E. Callahan, Thomas M. Folks, Paul Sandstrom, Shambavi Subbarao, Jennifer Brown, Walid Heneine, William M. Switzer
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The present invention comprises spumavirus isolated from humans. More specifically, the spumavirus of the present invention was isolated from humans who had exposure to nonhuman primates. Importantly, the spumavirus of the present invention or antibodies to the spumavirus can be used to detect the presence of spumavirus or antibodies in body fluids, for pathogenicity studies of related viruses, and as a vector for gene therapies. The spumavirus of the invention can also be used for treatment of conditions in humans due to the presence of rapidly dividing cells and for recombinant live virus vaccination.
A method for detecting a spumavirus infection, comprising, contacting a sample of nucleic acids with a probe comprising a sequence of SFVHu-1.
The method of claim 15, wherein the probe sequence comprises fragments of Seq. ID 1.
The method of claim 15, wherein the probe sequence comprises fragments of Seq. ID 2.
The method of claim 15, wherein the probe sequence comprises fragments of Seq. ID 3.
The method of claim 15, wherein the probe sequence comprises fragments of Seq. ID 4.
The method of claim 15, wherein the probe sequence comprises fragments of Seq. ID 5.
Dependencies are inferred from the claim text.