RelA-associated inhibitor, process for producing the same and utilization thereof
AssigneeOno Pharmaceutical Co., Ltd.
InventorTakashi Okamoto
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Abstract
Human RelA-associated inhibitor (RAI) comprising 351 amino acid, process for producing it, cDNA encoding it, fragment capable of hybridizing selectively to the cDNA sequence, plasmid for expression and duplication comprising the cDNA, host cell transformed with the plasmid, antibody against the polypeptide, pharmaceutical composition comprising the polypeptide or the antibody against it and method for diagnosis of diseases using the antibody against the RAI. RAI of the invention is capable of binding to p65, which is a submit of transcription factor NFκB, therefore, it is thought to be useful for treatment and/or prevention of various diseases.
Claims13
A polypeptide that comprising an amino acid sequence shown in SEQ ID NO. 1 in substantially purified form, homologue thereof, fragment thereof or homologue of the fragment.
Dependencies are inferred from the claim text.