Molecular recognition of materials
OwnerAngela M. Belcherinventor
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Abstract
The present invention includes methods for selective binding of inorganic materials and the compositions that made up of the selecting agent and the target materials. One form of the present invention is a method for selecting crystal-binding peptides with binding specificity including the steps of contacting one or more amino acid oligomers with one or more single-crystals of a semiconductor material so that the oligomers may bind to the crystal and eluting the bound amino acid oligomers from the single-crystals.
Claims62
A method for selecting crystal-binding peptides with binding specificity comprising the steps of:
- contacting one or more amino acid oligomers with one or more single-crystals of a semiconductor material so that the oligomers may bind to the crystal;
- and
- eluting the bound amino acid oligomers from the single-crystals.
An amino acid sequence for the binding GaAs (100) chosen from the group consisting of Seq. ID Nos. 1 through 11, inclusive.
A method for selecting amino acid sequences with binding specificity comprising the steps of:
- contacting one or more amino acid oligomers with one or more single-crystals of a magnetic, mineral or optical material so that the oligomers may bind to the crystal;
- and
- eluting the bound amino acid oligomers from the single-crystals.
A method for selecting crystal-bonding amino acids comprising the steps of:
- contacting one or more amino acid oligomers with one or more crystals of a target material so that the oligomers may bind to the crystal;
- and
- eluting the bound amino acid oligomers from the crystals.
An amino acid sequence for the binding GaAs (100) chosen from the group consisting of Seq. ID Nos. 1 to 11.
A specificity structure comprising:
- one or more single crystals of gallium arsenide;
- and
- a selective binding amino acid sequence.
A specificity structure comprising:
- one or more single crystals of cadmium sulfide;
- and
- a selective binding amino acid sequence.
A specificity structure comprising:
- one or more single crystals of zinc sulfide;
- and
- a selective binding amino acid sequence.
A specificity structure comprising:
- one or more single crystals of lead sulfide;
- and
- a selective binding amino acid sequence.
A crystal binding amino acid oligomers comprising the sequence motif (ser/tyr/thr)-(arg/asp/ser)-Xaa-(ser/asn/glu/arg/thr)-Xaa-Xaa-(ser/thr/glu/asp)-(ser/thr/tyr).
A crystal binding amino acid oligomers comprising the sequence motif Xaa-Xaa-(ser/tyr/thr)-(arg/asp/ser)-Xaa -(ser/asn/glu/arg/thr)-Xaa-Xaa-(ser/thr/glu/asp)-(ser/thr/tyr) -(ser/thr/his)-Xaa-Xaa.
A method of determining a binding motif comprising the steps:
- contacting a binding library with one or more crystals of a target material to allow components of the library to bind via a binding region to the crystals;
- eluting off bound components;
- and
- sequencing the eluted components.
Dependencies are inferred from the claim text.